Glossary of Terms
Home Up DEVELOPING A GENETIC MARKER Analogy for a Polygenic Trait with a Single Locus of Large Effect Clinical and Genetic Advances - Canine Epilepsy by George Brewer, MD AKC GRANT INFORMATION Be Part of the Solution! Glossary of Terms

Glossary of Terms

Autosomal
Phenotypic trait or gene NOT associated with either the X or Y sex chromosome; i.e., not sex-linked.
 
Genome
Complete set of chromosomes carried in a cell.
 
Gibbs sampling
Method of calculating the genetic merit of dogs that takes advantage of fast computers. The process itself is just a computer-based method for integrating a function without having to find the antiderivative.
 
Idiopathic
Arising spontaneously with no obvious external cause (e.g., genetic as opposed to trauma-induced).
 
Locus (plural - loci)
Site or position on a chromosome where a particular gene or DNA sequence resides. Often used interchangeably with the term 'gene', but locus is more generic.
 
Microsatellite
As used here, a region of the DNA that can be consistently identified, using a laboratory procedure, across all individuals in a single breed. Microsatellites themselves are repetitive DNA sequences that are randomly distributed throughout the mammalian genome, tend to be highly polymorphic, and are short DNA segments.
 
Polygenic
Phenotypic trait whose expression is controlled by, or associated with, more than one gene.
 
Polymorphic
Presence of several common, alternate forms of a genetic characteristic in a population.
 
Recessive
Trait that requires two mutant copies of the gene (i.e., alleles) in order for the disorder to be expressed; must be homozygous for the mutant allele.
 

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